JAK3-IN-14, CAS [[454234-24-3]]

Product Overview

• Article Name: JAK3-IN-14, CAS [[454234-24-3]]
• Biozol Catalog Number: BYT-ORB1685591
• Supplier Catalog Number: orb1685591
• Alternative Catalog Number: BYT-ORB1685591-1, BYT-ORB1685591-1, BYT-ORB1685591-10, BYT-ORB1685591-100, BYT-ORB1685591-25, BYT-ORB1685591-5, BYT-ORB1685591-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: (3Z)5(pyridin3yl)3[(1Hpyrrol2yl)methylidene]2,3dihydro1Hindol2one, FLT3, JAK3-IN-14

Product Description

JAK3-IN-14 is a potent, selective, and orally bioavailable small molecule inhibitor of FLT3, demonstrating nanomolar IC50 values against FLT3-WT, FLT3-D835Y, and FLT3-D835H mutants. It is a valuable research tool for investigating FLT3-driven pathologies, such as acute myeloid leukemia (AML), in both cellular and animal models.

Product Properties

• Molecular Weight: 287.32
• Purity: 98.98% (May vary between batches)
• CAS Number: [454234-24-3]
• Formula: C18H13N3O
• Target: JAK,FLT

Application Notes

• Application Notes: Solubility: DMSO:50 mg/mL (174.02 mM)