Varlitinib, CAS [[845272-21-1]]

Produktübersicht

• Artikelname: Varlitinib, CAS [[845272-21-1]]
• Artikelnummer: BYT-ORB1685624
• Hersteller Artikelnummer: orb1685624
• Alternativnummer: BYT-ORB1685624-1, BYT-ORB1685624-1, BYT-ORB1685624-10, BYT-ORB1685624-25, BYT-ORB1685624-5, BYT-ORB1685624-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: ARRY 334543, ARRY334543, ARRY-334543, ASLAN001, ASLAN-001, ASLAN 001, HER1, HER2, HER4, Varlitinib

Produktbeschreibung

Varlitinib (ASLAN001) is a reversible pan-EGFR inhibitor with potent activity against HER1 (IC50=7 nM), HER2 (IC50=2 nM), and HER4 (IC50=4 nM). It is a research tool used in vitro and in vivo for studying EGFR-driven cancers, including biliary tract and gastric malignancies.

Produkteigenschaften

• Molekulargewicht: 466.94
• Reinheit: 99.70% (May vary between batches)
• CAS Nummer: [845272-21-1]
• Formel: C22H19ClN6O2S
• Target-Kategorie: HER,EGFR

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.28 mM),Ethanol:< 1 mg/mL (insoluble or slightly soluble),DMSO:31.5 mg/mL (67.46 mM)