Varlitinib, CAS [[845272-21-1]]

Product Overview

• Article Name: Varlitinib, CAS [[845272-21-1]]
• Biozol Catalog Number: BYT-ORB1685624
• Supplier Catalog Number: orb1685624
• Alternative Catalog Number: BYT-ORB1685624-1, BYT-ORB1685624-1, BYT-ORB1685624-10, BYT-ORB1685624-25, BYT-ORB1685624-5, BYT-ORB1685624-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: ARRY 334543, ARRY334543, ARRY-334543, ASLAN001, ASLAN-001, ASLAN 001, HER1, HER2, HER4, Varlitinib

Product Description

Varlitinib (ASLAN001) is a reversible pan-EGFR inhibitor with potent activity against HER1 (IC50=7 nM), HER2 (IC50=2 nM), and HER4 (IC50=4 nM). It is a research tool used in vitro and in vivo for studying EGFR-driven cancers, including biliary tract and gastric malignancies.

Product Properties

• Molecular Weight: 466.94
• Purity: 99.70% (May vary between batches)
• CAS Number: [845272-21-1]
• Formula: C22H19ClN6O2S
• Target: HER,EGFR

Application Notes

• Application Notes: Solubility: H2O:< 1 mg/mL (insoluble or slightly soluble),10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.28 mM),Ethanol:< 1 mg/mL (insoluble or slightly soluble),DMSO:31.5 mg/mL (67.46 mM)