NSC-697923 is a UBE2N (Ubc13) inhibitor that induces neuroblastoma cell death via p53 nuclear import in wild-type cells or JNK-mediated apoptosis in p53-mutant cells. It also suppresses DNA damage and NF-kappaB signaling, demonstrating antitumor activity in vitro. This compound is a useful research tool for studying ubiquitination, apoptosis pathways, and neuroblastoma models.