NSC697923, CAS [[343351-67-7]]

Product Overview

• Article Name: NSC697923, CAS [[343351-67-7]]
• Biozol Catalog Number: BYT-ORB1685641
• Supplier Catalog Number: orb1685641
• Alternative Catalog Number: BYT-ORB1685641-1, BYT-ORB1685641-10, BYT-ORB1685641-100, BYT-ORB1685641-25, BYT-ORB1685641-5, BYT-ORB1685641-50, BYT-ORB1685641-500
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Ubc13, NSC697923, NSC-697923, NSC 697923, 2-[(4-methylphenyl)sulfonyl]-5-nitrofuran, E3Enzyme, E3 Enzyme, E2Enzyme, E2 Enzyme, E1 Enzyme, E1Enzyme

Product Description

NSC-697923 is a UBE2N (Ubc13) inhibitor that induces neuroblastoma cell death via p53 nuclear import in wild-type cells or JNK-mediated apoptosis in p53-mutant cells. It also suppresses DNA damage and NF-kappaB signaling, demonstrating antitumor activity in vitro. This compound is a useful research tool for studying ubiquitination, apoptosis pathways, and neuroblastoma models.

Product Properties

• Molecular Weight: 267.26
• Purity: 99.84% (May vary between batches)
• CAS Number: [343351-67-7]
• Formula: C11H9NO5S
• Target: E1/E2/E3 Enzyme,Apoptosis

Application Notes

• Application Notes: Solubility: DMSO:180 mg/mL (673.5 mM),Ethanol:6.7 mg/mL (25.07 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (18.71 mM)