CM121 is a potent, reversible, and active-site directed inhibitor of ALDH1A2, with an IC50 of 0.54 µM and a Kd of 1.1 µM, mediated by hydrophobic interactions. This small molecule is a valuable chemical probe for studying retinoic acid biosynthesis in cancer stem cell biology and developmental research, applicable in both in vitro and in vivo models.
Molekulargewicht:
460.48
CAS Nummer:
[2204230-40-8]
Formel:
C24H17FN4O3S
Target-Kategorie:
Others,Dehydrogenase
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
