CM121 is a potent, reversible, and active-site directed inhibitor of ALDH1A2, with an IC50 of 0.54 µM and a Kd of 1.1 µM, mediated by hydrophobic interactions. This small molecule is a valuable chemical probe for studying retinoic acid biosynthesis in cancer stem cell biology and developmental research, applicable in both in vitro and in vivo models.
Molecular Weight:
460.48
CAS Number:
[2204230-40-8]
Formula:
C24H17FN4O3S
Target:
Others,Dehydrogenase
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