Rubone is a natural chalcone that upregulates miR-34a expression in a p53-dependent manner, leading to the downregulation of oncogenic targets like Bcl-2 and cyclin-D1. This activity inhibits tumor cell proliferation and has demonstrated efficacy in reversing chemoresistance in prostate cancer and suppressing hepatocellular carcinoma growth in preclinical models.
Molekulargewicht:
374.38
Reinheit:
98.92% (May vary between batches)
CAS Nummer:
[73694-15-2]
Formel:
C20H22O7
Target-Kategorie:
MicroRNA
Anwendungsbeschreibung:
Solubility: DMSO:1 mg/mL (2.67 mM)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten