Rubone, CAS [[73694-15-2]]

Product Overview

• Article Name: Rubone, CAS [[73694-15-2]]
• Biozol Catalog Number: BYT-ORB1702848
• Supplier Catalog Number: orb1702848
• Alternative Catalog Number: BYT-ORB1702848-1, BYT-ORB1702848-10, BYT-ORB1702848-25, BYT-ORB1702848-5, BYT-ORB1702848-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: 2-Hydroxy-2,4,4,5,6-pentamethoxychalcone, Rubone

Product Description

Rubone is a natural chalcone that upregulates miR-34a expression in a p53-dependent manner, leading to the downregulation of oncogenic targets like Bcl-2 and cyclin-D1. This activity inhibits tumor cell proliferation and has demonstrated efficacy in reversing chemoresistance in prostate cancer and suppressing hepatocellular carcinoma growth in preclinical models.

Product Properties

• Molecular Weight: 374.38
• Purity: 98.92% (May vary between batches)
• CAS Number: [73694-15-2]
• Formula: C20H22O7
• Target: MicroRNA

Application Notes

• Application Notes: Solubility: DMSO:1 mg/mL (2.67 mM)