3-substituted indolin-2-one 16f, PDGFR1, PDGFR2, PDGFRbeta, SU16f, SU-16F, SU 16F
SU16f is a potent and selective PDGFRbeta inhibitor (IC50 = 10 nM) that blocks PDGFRbeta-mediated signaling. Its application in research includes in vitro studies demonstrating inhibition of gastric cancer cell proliferation and migration driven by MSC-conditioned medium, highlighting its utility in oncology and stromal interaction research.
Molekulargewicht:
386.44
Reinheit:
98.38% (May vary between batches)
CAS Nummer:
[251356-45-3]
Formel:
C24H22N2O3
Target-Kategorie:
PDGFR
Anwendungsbeschreibung:
Solubility: DMSO:25 mg/mL (64.69 mM)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten