3-substituted indolin-2-one 16f, PDGFR1, PDGFR2, PDGFRbeta, SU16f, SU-16F, SU 16F
SU16f is a potent and selective PDGFRbeta inhibitor (IC50 = 10 nM) that blocks PDGFRbeta-mediated signaling. Its application in research includes in vitro studies demonstrating inhibition of gastric cancer cell proliferation and migration driven by MSC-conditioned medium, highlighting its utility in oncology and stromal interaction research.
Molecular Weight:
386.44
Purity:
98.38% (May vary between batches)
CAS Number:
[251356-45-3]
Formula:
C24H22N2O3
Target:
PDGFR
Application Notes:
Solubility: DMSO:25 mg/mL (64.69 mM)
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