GSK2945 is a potent and selective antagonist of Rev-erbalpha/REV-ERBalpha, with EC50 values of 21.5 µM and 20.8 µM respectively. It promotes cholesterol metabolism by upregulating CYP7A1, making it a valuable tool for studying circadian metabolism and liver function in biochemical and pharmacological research.
Molekulargewicht:
421.34
CAS Nummer:
[1438071-12-5]
Formel:
C20H18Cl2N2O2S
Target-Kategorie:
Cytochromes P450,Others
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