GSK2945 is a potent and selective antagonist of Rev-erbalpha/REV-ERBalpha, with EC50 values of 21.5 µM and 20.8 µM respectively. It promotes cholesterol metabolism by upregulating CYP7A1, making it a valuable tool for studying circadian metabolism and liver function in biochemical and pharmacological research.
Molecular Weight:
421.34
CAS Number:
[1438071-12-5]
Formula:
C20H18Cl2N2O2S
Target:
Cytochromes P450,Others
* VAT and and shipping costs not included. Errors and price changes excepted
