GNE-0439, CAS [[1241902-40-8]]

Produktübersicht

• Artikelname: GNE-0439, CAS [[1241902-40-8]]
• Artikelnummer: BYT-ORB1709573
• Hersteller Artikelnummer: orb1709573
• Alternativnummer: BYT-ORB1709573-1,BYT-ORB1709573-10,BYT-ORB1709573-100,BYT-ORB1709573-25,BYT-ORB1709573-5,BYT-ORB1709573-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: Nav1.7, GNE0439, GNE-0439, GNE 0439

Produktbeschreibung

GNE-0439 is a novel, state-dependent Nav1.7 inhibitor (IC50=0.34 µM) with significant selectivity over Nav1.5. Its unique carboxylic acid moiety binds outside the pore, differentiating it from VSD4-targeting compounds. This tool compound is valuable for in vitro electrophysiology and pain research to study sodium channel pharmacology and gating mechanisms.

Produkteigenschaften

• Molekulargewicht: 345.48
• Reinheit: 99.60% (May vary between batches)
• CAS Nummer: [1241902-40-8]
• Formel: C21H31NO3
• Target-Kategorie: Sodium Channel

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: DMSO:105 mg/mL (303.92 mM),10% DMSO+40% PEG300+5% Tween-80+45% Saline:4 mg/mL (11.58 mM)