GNE-0439, CAS [[1241902-40-8]]

Product Overview

• Article Name: GNE-0439, CAS [[1241902-40-8]]
• Biozol Catalog Number: BYT-ORB1709573
• Supplier Catalog Number: orb1709573
• Alternative Catalog Number: BYT-ORB1709573-1,BYT-ORB1709573-10,BYT-ORB1709573-100,BYT-ORB1709573-25,BYT-ORB1709573-5,BYT-ORB1709573-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: Nav1.7, GNE0439, GNE-0439, GNE 0439

Product Description

GNE-0439 is a novel, state-dependent Nav1.7 inhibitor (IC50=0.34 µM) with significant selectivity over Nav1.5. Its unique carboxylic acid moiety binds outside the pore, differentiating it from VSD4-targeting compounds. This tool compound is valuable for in vitro electrophysiology and pain research to study sodium channel pharmacology and gating mechanisms.

Product Properties

• Molecular Weight: 345.48
• Purity: 99.60% (May vary between batches)
• CAS Number: [1241902-40-8]
• Formula: C21H31NO3
• Target: Sodium Channel

Application Notes

• Application Notes: Solubility: DMSO:105 mg/mL (303.92 mM),10% DMSO+40% PEG300+5% Tween-80+45% Saline:4 mg/mL (11.58 mM)