CDK8-IN-13 is a potent, selective, and orally bioavailable CDK8 inhibitor (IC50 = 51.9 nM). It induces apoptosis, suppresses p-STAT1 S727 and p-STAT5 S726, and demonstrates anti-tumor activity in research models, supporting its use in oncology and signal transduction studies.
Molekulargewicht:
237.26
Reinheit:
99.28% (May vary between batches)
CAS Nummer:
[918523-75-8]
Formel:
C14H11N3O
Target-Kategorie:
Apoptosis,CDK
Anwendungsbeschreibung:
Solubility: DMSO:112.5 mg/mL (474.16 mM)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten