CDK8-IN-13 is a potent, selective, and orally bioavailable CDK8 inhibitor (IC50 = 51.9 nM). It induces apoptosis, suppresses p-STAT1 S727 and p-STAT5 S726, and demonstrates anti-tumor activity in research models, supporting its use in oncology and signal transduction studies.
Molecular Weight:
237.26
Purity:
99.28% (May vary between batches)
CAS Number:
[918523-75-8]
Formula:
C14H11N3O
Target:
Apoptosis,CDK
Application Notes:
Solubility: DMSO:112.5 mg/mL (474.16 mM)
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