11beta-HSD1 inibitor 19, CAS [[946400-19-7]]

Artikelnummer: BYT-ORB1737472
Artikelname: 11beta-HSD1 inibitor 19, CAS [[946400-19-7]]
Artikelnummer: BYT-ORB1737472
Hersteller Artikelnummer: orb1737472
Alternativnummer: BYT-ORB1737472-1, BYT-ORB1737472-10, BYT-ORB1737472-100, BYT-ORB1737472-200, BYT-ORB1737472-25, BYT-ORB1737472-5, BYT-ORB1737472-50
Hersteller: Biorbyt
Kategorie: Biochemikalien
Alternative Synonym: HSD1, 3chloro4[[(2R)4[4fluoro2(trifluoromethyl)phenyl]2methyl1piperazinyl]sulfonyl]Benzonitrile, 11beta-HSD1 inibitor 19, 11b-HSD1 inibitor 19, 11beta-HSD1 inibitor 19
This potent small molecule inhibitor, designated as compound 19, demonstrates high inhibitory activity against both human and mouse 11beta-HSD1 enzymes, with IC50 values of 16 nM and 10 nM, respectively. It is a valuable research tool for investigating glucocorticoid metabolism in metabolic and inflammatory disease models, both in vitro and in vivo.
Molekulargewicht: 461.86
Reinheit: 99.58% (May vary between batches)
CAS Nummer: [946400-19-7]
Formel: C19H16ClF4N3O2S
Target-Kategorie: Dehydrogenase
Anwendungsbeschreibung: Solubility: DMSO:55 mg/mL (119.08 mM)