This potent small molecule inhibitor, designated as compound 19, demonstrates high inhibitory activity against both human and mouse 11beta-HSD1 enzymes, with IC50 values of 16 nM and 10 nM, respectively. It is a valuable research tool for investigating glucocorticoid metabolism in metabolic and inflammatory disease models, both in vitro and in vivo.
Molekulargewicht:
461.86
Reinheit:
99.58% (May vary between batches)
CAS Nummer:
[946400-19-7]
Formel:
C19H16ClF4N3O2S
Target-Kategorie:
Dehydrogenase
Anwendungsbeschreibung:
Solubility: DMSO:55 mg/mL (119.08 mM)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten