11beta-HSD1 inibitor 19, CAS [[946400-19-7]]

Product Overview

• Article Name: 11beta-HSD1 inibitor 19, CAS [[946400-19-7]]
• Biozol Catalog Number: BYT-ORB1737472
• Supplier Catalog Number: orb1737472
• Alternative Catalog Number: BYT-ORB1737472-1, BYT-ORB1737472-10, BYT-ORB1737472-100, BYT-ORB1737472-200, BYT-ORB1737472-25, BYT-ORB1737472-5, BYT-ORB1737472-50
• Manufacturer: Biorbyt
• Category: Biochemikalien
• Alternative Names: HSD1, 3chloro4[[(2R)4[4fluoro2(trifluoromethyl)phenyl]2methyl1piperazinyl]sulfonyl]Benzonitrile, 11beta-HSD1 inibitor 19, 11b-HSD1 inibitor 19, 11beta-HSD1 inibitor 19

Product Description

This potent small molecule inhibitor, designated as compound 19, demonstrates high inhibitory activity against both human and mouse 11beta-HSD1 enzymes, with IC50 values of 16 nM and 10 nM, respectively. It is a valuable research tool for investigating glucocorticoid metabolism in metabolic and inflammatory disease models, both in vitro and in vivo.

Product Properties

• Molecular Weight: 461.86
• Purity: 99.58% (May vary between batches)
• CAS Number: [946400-19-7]
• Formula: C19H16ClF4N3O2S
• Target: Dehydrogenase

Application Notes

• Application Notes: Solubility: DMSO:55 mg/mL (119.08 mM)