8-Azanebularine is a potent inhibitor of human ADAR2, exhibiting high-affinity binding (KD=2 nM) when incorporated into RNA and effectively blocking the editing reaction (IC50=15 mM). This makes it a valuable chemical tool for studying ADAR-mediated RNA editing mechanisms in both in vitro and cellular research applications.
Molekulargewicht:
253.21
CAS Nummer:
[38874-46-3]
Formel:
C9H11N5O4
Target-Kategorie:
Adenosine Deaminase,Others
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten