8-Azanebularine is a potent inhibitor of human ADAR2, exhibiting high-affinity binding (KD=2 nM) when incorporated into RNA and effectively blocking the editing reaction (IC50=15 mM). This makes it a valuable chemical tool for studying ADAR-mediated RNA editing mechanisms in both in vitro and cellular research applications.
Molecular Weight:
253.21
CAS Number:
[38874-46-3]
Formula:
C9H11N5O4
Target:
Adenosine Deaminase,Others
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