Amyloid-Forming peptide GNNQQNY, CAS [[339091-39-3]] Preis auf Anfrage

Produktübersicht

• Artikelname: Amyloid-Forming peptide GNNQQNY, CAS [[339091-39-3]] Preis auf Anfrage
• Artikelnummer: BYT-ORB1941648
• Hersteller Artikelnummer: orb1941648
• Alternativnummer: BYT-ORB1941648-5,BYT-ORB1941648-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien

Produktbeschreibung

Amyloid-Forming peptide GNNQQNY, a biologically active heptapeptide derived from the N-terminal prion-determining domain of yeast Sup35, is instrumental in amyloid fibril formation. Its atomic oligomeric structure has been detailed, serving as an excellent model for investigating early-stage aggregation. The peptide can form three stable beta-sheet structures: in-register parallel, off-register parallel, and anti-parallel. Notably, the in-register parallel dimer aligns closely with amyloid beta-sheet architecture, relying on fewer interpeptide hydrogen bonds and emphasizing hydrophobic interactions, which enhances conformational entropy relative to the anti-parallel arrangement.

Produkteigenschaften

• Molekulargewicht: 836.81
• CAS Nummer: [339091-39-3]
• Formel: C33H48N12O14
• Target-Kategorie: Beta Amyloid