Neratinib maleate is an irreversible, orally bioavailable inhibitor selectively targeting HER2 (IC50=59 nM) and EGFR (IC50=92 nM). It is widely used in preclinical cancer research, demonstrating antitumor activity in both in vitro assays and in vivo models for breast, prostate, and other solid tumors.
Molekulargewicht:
673.11
Reinheit:
99.99% (May vary between batches)
CAS Nummer:
[915942-22-2]
Formel:
C34H33ClN6O7
Target-Kategorie:
HER,EGFR
Anwendungsbeschreibung:
Solubility: DMSO:225 mg/mL (334.27 mM)
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten