Neratinib maleate is an irreversible, orally bioavailable inhibitor selectively targeting HER2 (IC50=59 nM) and EGFR (IC50=92 nM). It is widely used in preclinical cancer research, demonstrating antitumor activity in both in vitro assays and in vivo models for breast, prostate, and other solid tumors.
Molecular Weight:
673.11
Purity:
99.99% (May vary between batches)
CAS Number:
[915942-22-2]
Formula:
C34H33ClN6O7
Target:
HER,EGFR
Application Notes:
Solubility: DMSO:225 mg/mL (334.27 mM)
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