SLB1122168 is a potent and selective inhibitor of the S1P transporter Spns2 (IC50 = 94 nM for mouse). At 10 mg/kg in mice, it effectively reduces lymphocyte counts in circulation without affecting plasma S1P levels, making it a valuable tool for researching S1P signaling and immunomodulation in vivo.
Molekulargewicht:
394.00
Formel:
C22H35N3O.HCl
Target-Kategorie:
Others
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten