SLB1122168 is a potent and selective inhibitor of the S1P transporter Spns2 (IC50 = 94 nM for mouse). At 10 mg/kg in mice, it effectively reduces lymphocyte counts in circulation without affecting plasma S1P levels, making it a valuable tool for researching S1P signaling and immunomodulation in vivo.
Molecular Weight:
394.00
Formula:
C22H35N3O.HCl
Target:
Others
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