Motapizone (NAT 05-239) is a selective phosphodiesterase 3 (PDE3) inhibitor. It elevates intracellular cAMP levels, leading to the suppression of cytokine release in LPS-stimulated human alveolar macrophages and inhibition of human platelet aggregation. This mechanism supports its research applications in studying inflammatory lung diseases and thrombosis in both cellular and animal models.
Molekulargewicht:
260.32
Reinheit:
95.26% (May vary between batches)
CAS Nummer:
[90697-57-7]
Formel:
C12H12N4OS
Target-Kategorie:
Others,Platelet aggregation,PDE,cAMP
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten