Dot1L-IN-1 TFA is a highly potent and selective Dot1L inhibitor with sub-nanomolar activity. It effectively reduces H3K79 dimethylation and suppresses HoxA9 promoter activity in cellular assays, making it a valuable chemical probe for epigenetic research in oncology and hematology, including studies of MLL-rearranged leukemia.
Molekulargewicht:
760.23
Formel:
C34H37ClF3N9O4S
Target-Kategorie:
Histone Methyltransferase,Others
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
