VHL Ligand-Linker Conjugates 17 are bifunctional chemical tools consisting of a VHL E3 ligase ligand connected to a linker, designed for constructing PROTAC degraders. They serve as key intermediates in synthesizing potent degraders like ARD-266, which effectively degrades the androgen receptor in cancer research, as demonstrated in both cellular and in vivo studies.
Molekulargewicht:
654.75
Formel:
C37H42N4O7
Target-Kategorie:
Others,E3 Ligase Ligand-Linker Conjugates
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
