Antileishmanial agent-19 Preis auf Anfrage

Artikelnummer: BYT-ORB2277932
Artikelname: Antileishmanial agent-19 Preis auf Anfrage
Artikelnummer: BYT-ORB2277932
Hersteller Artikelnummer: orb2277932
Alternativnummer: BYT-ORB2277932-50,BYT-ORB2277932-5
Hersteller: Biorbyt
Kategorie: Biochemikalien
Compound F27 (Antileishmanial agent-19) is an antileishmanial compound effective against L. donovani promastigotes, demonstrating an IC50 of 3.39 µM. It functions by inhibiting the Leishmania prolyl-tRNA synthetase and disrupting the host PI3K/Akt/CREB axis-mediated IL-10 secretion. Additionally, Compound F27 promotes autophagy-mediated apoptosis in L. donovani promastigotes and has been shown to reduce parasite burden in L.d-infected animals.
Molekulargewicht: 386.4
Formel: C22H18N4O3
Target-Kategorie: Parasite