Antileishmanial agent-19 Preis auf Anfrage

Catalog Number: BYT-ORB2277932
Article Name: Antileishmanial agent-19 Preis auf Anfrage
Biozol Catalog Number: BYT-ORB2277932
Supplier Catalog Number: orb2277932
Alternative Catalog Number: BYT-ORB2277932-50,BYT-ORB2277932-5
Manufacturer: Biorbyt
Category: Biochemikalien
Compound F27 (Antileishmanial agent-19) is an antileishmanial compound effective against L. donovani promastigotes, demonstrating an IC50 of 3.39 µM. It functions by inhibiting the Leishmania prolyl-tRNA synthetase and disrupting the host PI3K/Akt/CREB axis-mediated IL-10 secretion. Additionally, Compound F27 promotes autophagy-mediated apoptosis in L. donovani promastigotes and has been shown to reduce parasite burden in L.d-infected animals.
Molecular Weight: 386.4
Formula: C22H18N4O3
Target: Parasite