PROTAC BTK Degraders-5 (Compound 3e) is a selective Brutons tyrosine kinase (BTK) degrader with a DC50 of 7.0 nM in JeKo-1 cells, demonstrating specificity by not affecting CRBN neosubstrates. It also exhibits antiproliferative effects on various lymphoma cell lines, underscoring its potential application in chronic lymphoid malignancies research.
Molekulargewicht:
958.52
Formel:
C52H57ClFN9O6
Target-Kategorie:
BTK
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
