SB-1295, an orally active CDK9/T1 inhibitor with an IC50 of 0.17 µM, exhibits antiproliferative effects on HCT 116 and MIA PaCa-2 cells. It promotes cell death in MIA PaCa-2 by elevating intracellular ROS levels, diminishing mitochondrial membrane potential, and triggering apoptosis. This compound holds potential for cancer research.
Molekulargewicht:
443.88
Formel:
C23H22ClNO6
Target-Kategorie:
Reactive Oxygen Species
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
