MCI, a chemical compound demonstrating significant anti-inflammatory effects, particularly in collagen-induced arthritis (CIA) models, modulates inflammation through macrophage reprogramming by enhancing ROS scavenging and promoting COX-2 downregulation. It effectively inhibits COX-2, exhibiting an IC50 of 1.23 µM. Additionally, MCI holds potential for research applications in rheumatoid arthritis (RA).
Molekulargewicht:
934.39
Formel:
C45H52ClN7O13
Target-Kategorie:
Reactive Oxygen Species
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten