MCI, a chemical compound demonstrating significant anti-inflammatory effects, particularly in collagen-induced arthritis (CIA) models, modulates inflammation through macrophage reprogramming by enhancing ROS scavenging and promoting COX-2 downregulation. It effectively inhibits COX-2, exhibiting an IC50 of 1.23 µM. Additionally, MCI holds potential for research applications in rheumatoid arthritis (RA).
Molecular Weight:
934.39
Formula:
C45H52ClN7O13
Target:
Reactive Oxygen Species
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