JPS016 is a benzamide-based VHL-recruiting PROTAC that induces potent degradation of class I HDACs, specifically HDAC1 and HDAC2. This degradation leads to altered gene expression and enhanced apoptosis in cellular models like HCT116, supporting its use as a chemical probe for oncology and epigenetics research.
Molekulargewicht:
1012.14
Formel:
C50H64F3N7O10S
Target-Kategorie:
HDAC,PROTACs
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
