Val-Ala-PAB-MMAE, CAS [[1912408-92-4]]

Produktübersicht

• Artikelname: Val-Ala-PAB-MMAE, CAS [[1912408-92-4]]
• Artikelnummer: BYT-ORB2279056
• Hersteller Artikelnummer: orb2279056
• Alternativnummer: BYT-ORB2279056-1,BYT-ORB2279056-10,BYT-ORB2279056-25,BYT-ORB2279056-5,BYT-ORB2279056-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien
• Alternative Synonym: DrugLinkerConjugatesforADC, DrugLinker Conjugates for ADC

Produktbeschreibung

Val-Ala-PAB-MMAE is a cathepsin B-cleavable ADC linker-payload conjugate. Upon intracellular cleavage, it releases the cytotoxic agent MMAE to disrupt microtubule assembly, inducing apoptosis in targeted cells. This construct is widely used in ADC research for evaluating antitumor efficacy in both in vitro and in vivo models.

Produkteigenschaften

• Molekulargewicht: 1037.33
• Reinheit: 99.02% (May vary between batches)
• CAS Nummer: [1912408-92-4]
• Formel: C55H88N8O11
• Target-Kategorie: Microtubule Associated,Drug-Linker Conjugates for ADC

Anwendungsbeschreibung

• Anwendungsbeschreibung: Solubility: DMSO:80 mg/mL (77.12 mM),10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (3.18 mM)