E0924G is a potent and orally active PPARdelta agonist (EC50 = 2.82 µM) that upregulates osteoprotegerin expression (EC50 = 0.29 µM). It inhibits osteoclast differentiation and F-actin ring formation in vitro and has demonstrated efficacy in modulating bone density in preclinical models of osteoporosis, such as OVX and age-related bone loss.
Molekulargewicht:
232.24
CAS Nummer:
[2909474-29-7]
Formel:
C12H12N2O3
Target-Kategorie:
PPAR
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