FKK6 is a selective PXR agonist (EC50 = 1.2 µM) with favorable metabolic stability and high plasma protein binding. It inhibits PXR-mediated NF-kappaB signaling, demonstrating anti-inflammatory effects in vitro and in a DSS-induced colitis mouse model, making it a useful research tool for studying inflammatory and metabolic diseases.
Molekulargewicht:
402.47
CAS Nummer:
[2238839-34-2]
Formel:
C23H18N2O3S
Target-Kategorie:
NF-kappaB,Interleukin
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
