FKK6 is a selective PXR agonist (EC50 = 1.2 µM) with favorable metabolic stability and high plasma protein binding. It inhibits PXR-mediated NF-kappaB signaling, demonstrating anti-inflammatory effects in vitro and in a DSS-induced colitis mouse model, making it a useful research tool for studying inflammatory and metabolic diseases.
Molecular Weight:
402.47
CAS Number:
[2238839-34-2]
Formula:
C23H18N2O3S
Target:
NF-kappaB,Interleukin
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