PROTAC PARP1 degrader-3 (C6) is a potent and selective degrader of PARP1 (DC50 = 58.14 nM). It demonstrates cytotoxic activity in colon cancer cell lines like SW-620 and LOVO and shows synergistic effects with SN-38 in BRCA-mutated models, supporting its use in targeted protein degradation and combination therapy research.
Molekulargewicht:
896.13
Formel:
C52H65N9O5
Target-Kategorie:
PROTACs,PARP
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
