PARL-IN-2 (Compound 14) is a potent covalent inhibitor of the mitochondrial protease PARL (EC50 = 0.16 µM). Its inhibition robustly activates the PINK1/Parkin pathway, promoting mitophagy, and it serves as a critical research tool for studying mitochondrial quality control in cellular models.
Molekulargewicht:
365.42
Formel:
C22H23NO4
Target-Kategorie:
Mitophagy,PTEN
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
