AGU654 (Compound 44) is a potent and selective mPGES-1 inhibitor (IC50 = 2.9 nM) that suppresses PGE2 production in vitro in human macrophages and whole blood, and demonstrates anti-inflammatory, analgesic, and antipyretic efficacy in guinea pig models, supporting its use for researching inflammatory diseases and pain.
Molekulargewicht:
580.91
CAS Nummer:
[3038861-74-1]
Formel:
C27H19ClF6N4O2
Target-Kategorie:
PGE Synthase
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
