Chaetoglobosin E, CAS [[55945-74-9]] Preis auf Anfrage

Produktübersicht

• Artikelname: Chaetoglobosin E, CAS [[55945-74-9]] Preis auf Anfrage
• Artikelnummer: BYT-ORB3024473
• Hersteller Artikelnummer: orb3024473
• Alternativnummer: BYT-ORB3024473-10, BYT-ORB3024473-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien

Produktbeschreibung

Chaetoglobosin E is a ferroptosis inducer exhibiting significant cytotoxicity against the human tumor cell lines MDA-MB231 and A549, with IC50 values of 9.14 µM and 7.47 µM, respectively. It induces ferroptosis by downregulating GPX4 expression in A549 cells, leading to increased intracellular levels of Fe2+ (iron ions) and the lipid peroxidation product malondialdehyde (MDA), resulting in mitochondrial shrinkage and reduced or absent cristae. Chaetoglobosin E is applicable in cancer research.

Produkteigenschaften

• Molekulargewicht: 530.654
• CAS Nummer: [55945-74-9]
• Formel: C32H38N2O5
• Target-Kategorie: Ferroptosis