Chaetoglobosin E, CAS [[55945-74-9]] Preis auf Anfrage

Product Overview

• Article Name: Chaetoglobosin E, CAS [[55945-74-9]] Preis auf Anfrage
• Biozol Catalog Number: BYT-ORB3024473
• Supplier Catalog Number: orb3024473
• Alternative Catalog Number: BYT-ORB3024473-10, BYT-ORB3024473-50
• Manufacturer: Biorbyt
• Category: Biochemikalien

Product Description

Chaetoglobosin E is a ferroptosis inducer exhibiting significant cytotoxicity against the human tumor cell lines MDA-MB231 and A549, with IC50 values of 9.14 µM and 7.47 µM, respectively. It induces ferroptosis by downregulating GPX4 expression in A549 cells, leading to increased intracellular levels of Fe2+ (iron ions) and the lipid peroxidation product malondialdehyde (MDA), resulting in mitochondrial shrinkage and reduced or absent cristae. Chaetoglobosin E is applicable in cancer research.

Product Properties

• Molecular Weight: 530.654
• CAS Number: [55945-74-9]
• Formula: C32H38N2O5
• Target: Ferroptosis