Microtubulin-IN-1, CAS [[3025180-14-4]] Preis auf Anfrage

Produktübersicht

• Artikelname: Microtubulin-IN-1, CAS [[3025180-14-4]] Preis auf Anfrage
• Artikelnummer: BYT-ORB3028635
• Hersteller Artikelnummer: orb3028635
• Alternativnummer: BYT-ORB3028635-10, BYT-ORB3028635-50
• Hersteller: Biorbyt
• Kategorie: Biochemikalien

Produktbeschreibung

Microtubulin-IN-1 (Compound 8g) is an inhibitor of microtubulin, targeting the colchicine-binding site to disrupt tubulin integrity and induce upregulation of p53 protein expression. It exhibits antiproliferative activity across various cancer cell lines, including NCI-H460, BxPC-3, and HT-29, with IC50 values of 2.4, 1.6, and 2.07 nM, respectively. Additionally, Microtubulin-IN-1 induces cell cycle arrest at the G2/M phase and apoptosis in NCI-H460 cells.

Produkteigenschaften

• Molekulargewicht: 444.458
• CAS Nummer: [3025180-14-4]
• Formel: C25H21FN4O3
• Target-Kategorie: MDM-2/p53,Microtubule Associated,Apoptosis