Microtubulin-IN-1, CAS [[3025180-14-4]] Preis auf Anfrage

Product Overview

• Article Name: Microtubulin-IN-1, CAS [[3025180-14-4]] Preis auf Anfrage
• Biozol Catalog Number: BYT-ORB3028635
• Supplier Catalog Number: orb3028635
• Alternative Catalog Number: BYT-ORB3028635-10, BYT-ORB3028635-50
• Manufacturer: Biorbyt
• Category: Biochemikalien

Product Description

Microtubulin-IN-1 (Compound 8g) is an inhibitor of microtubulin, targeting the colchicine-binding site to disrupt tubulin integrity and induce upregulation of p53 protein expression. It exhibits antiproliferative activity across various cancer cell lines, including NCI-H460, BxPC-3, and HT-29, with IC50 values of 2.4, 1.6, and 2.07 nM, respectively. Additionally, Microtubulin-IN-1 induces cell cycle arrest at the G2/M phase and apoptosis in NCI-H460 cells.

Product Properties

• Molecular Weight: 444.458
• CAS Number: [3025180-14-4]
• Formula: C25H21FN4O3
• Target: MDM-2/p53,Microtubule Associated,Apoptosis