alpha-Tubulin polymerization-IN-1 Preis auf Anfrage

Artikelnummer: BYT-ORB3028658
Artikelname: alpha-Tubulin polymerization-IN-1 Preis auf Anfrage
Artikelnummer: BYT-ORB3028658
Hersteller Artikelnummer: orb3028658
Alternativnummer: BYT-ORB3028658-10, BYT-ORB3028658-50
Hersteller: Biorbyt
Kategorie: Sonstiges
alpha-Tubulin polymerization-IN-1 (Compound 8l) functions as an inhibitor of alpha-tubulin polymerization. This compound modulates the NRF2/KEAP-1 signaling pathway and induces ROS production in PC-3 cells, leading to apoptosis. It inhibits the proliferation of PC-3 cells with a GI50 of 0.17 µM, causing cell cycle arrest in the G2/M phase. Additionally, alpha-Tubulin polymerization-IN-1 demonstrates antitumor activity in mouse models.
Target-Kategorie: Apoptosis,Nrf2,ROS,Microtubule Associated,Reactive Oxygen Species