alpha-Tubulin polymerization-IN-1 Preis auf Anfrage
Biozol Catalog Number:
BYT-ORB3028658
Supplier Catalog Number:
orb3028658
Alternative Catalog Number:
BYT-ORB3028658-10, BYT-ORB3028658-50
Manufacturer:
Biorbyt
Category:
Sonstiges
alpha-Tubulin polymerization-IN-1 (Compound 8l) functions as an inhibitor of alpha-tubulin polymerization. This compound modulates the NRF2/KEAP-1 signaling pathway and induces ROS production in PC-3 cells, leading to apoptosis. It inhibits the proliferation of PC-3 cells with a GI50 of 0.17 µM, causing cell cycle arrest in the G2/M phase. Additionally, alpha-Tubulin polymerization-IN-1 demonstrates antitumor activity in mouse models.
Target:
Apoptosis,Nrf2,ROS,Microtubule Associated,Reactive Oxygen Species
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