DNA Alkylator/Crosslinker,EGFR Antibody, Unconjugated Preis auf Anfrage

Produktübersicht

• Artikelname: DNA Alkylator/Crosslinker,EGFR Antibody, Unconjugated Preis auf Anfrage
• Artikelnummer: BYT-ORB3031943-IH
• Hersteller Artikelnummer: orb3031943
• Alternativnummer: BYT-ORB3031943-1, BYT-ORB3031943-5
• Hersteller: Biorbyt
• Kategorie: Antikörper
• Konjugation: Unconjugated

Produktbeschreibung

MHES0488A is a selective humanized antibody targeting HER2, with a KD value of 0.8 nM. It constitutes the antibody portion of DHES0815A. Upon cellular internalization, MHES0488A is transported to lysosomes, releasing PBD-monoamide into the nucleus, where it alkylates DNA, inducing DNA damage and apoptosis. It shows potential for research in cancers such as HER2-positive breast cancer and gastric cancer.

Produkteigenschaften

• Target-Kategorie: EGFR,DNA Alkylator/Crosslinker